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Index > Protein center > Becn1(Gene name) > Rat
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  • Becn1 (Gene name),
  • Beclin-1 (Protein name ),  BECN1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Becn1;
    Protein name:
    Beclin-1;
    Alternative:
    Protein GT197;Coiled-coil myosin-like BCL2-interacting protein;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with BCL2 and BCL2L1 (By similarity). Interacts with GOPC and GRID2. Interacts with AMBRA1. Forms a complex with PIK3C3 and PIK3R4 and either UVRAG and KIAA0226/Rubicon, or with ATG14. UVRAG and ATG14 form mutually exclusive complexes through direct competition for BECN1-binding. The complex containing ATG14 upregulates autophagy, while the one containing Rubicon downregulates autophagy (By similarity). Interacts with VMP1. Interacts with PIK3CB.
    Function:
    Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense.
    Subcellular Location:
    Cytoplasm Golgi apparatus trans-Golgi network membrane Peripheral membrane protein Interaction with ATG14 promotes translocation to autophagosomes.
    Protein Attributes:
    Sequence length:
    448
    Sequence:
    50:
    MEGSKASSST | MQVSFVCQRC | SQPLKLDTSF | KILDRVTIQE | LTAPLLTTAQ | 
    100:
    AKPGESQEEE | ANSGEEPFIE | TRQDGVSRRF | IPPARMMSTE | SANSFTLIGE | 
    150:
    ASDGGTMENL | SRRLKVTGDL | FDIMSGQTDV | DHPLCEECTD | TLLDQLDTQL | 
    200:
    NVTENECQNY | KRCLEMLEQM | NEGDSEQLQR | ELKELALEEE | RLIQELEDVE | 
    250:
    KNRKVVAENL | EKVQAEAERL | DQEEAQYQRE | YSEFKRQQLE | LDDELKSVEN | 
    300:
    QMRYAQMQLD | KLKKTNVFNA | TFHIWHSGQF | GTINNFRLGR | LPSAPVEWNE | 
    350:
    INAAWGQTVL | LLHALANKMG | LKFQRYRLVP | YGNHSYLESL | TDKSKELPLY | 
    400:
    CSGGLRFFWD | NKFDHAMVAF | LDCVQQFKEE | VEKGETRFCL | PYRMDVEKGK | 
    448:
    IEDTGGSGGS | YSIKTQFNSE | EQWTKALKFM | LTNLKWGLAW | VSSQFYNK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Beclin-1
    Cat.:
    E1025h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rat Beclin-1
    Cat.:
    E1025m
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat Beclin-1
    Cat.:
    E1025r
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat Beclin-1
    Cat.:
    E1025p
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat Beclin-1
    Cat.:
    E1025b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat Beclin-1
    Cat.:
    E1025c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Beclin-1
    Cat.:
    U1025b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Beclin-1
    Cat.:
    U1025c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Beclin-1
    Cat.:
    U1025p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Beclin-1
    Cat.:
    U1025r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Beclin-1
    Cat.:
    U1025m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Beclin-1
    Cat.:
    U1025h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Rat Beclin-1
    Polyclonal Antibody for Rat Beclin-1
    Cat.:
    P1025Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Beclin-1
    Polyclonal Antibody for Rat Beclin-1
    Cat.:
    P1025Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Beclin-1
    Polyclonal Antibody for Rat Beclin-1
    Cat.:
    P1025Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Beclin-1
    Monoclonal Antibody for Rat Beclin-1
    Monoclonal Antibody for Rat Beclin-1
    Monoclonal Antibody for Rat Beclin-1
    Monoclonal Antibody for Rat Beclin-1
    Monoclonal Antibody for Rat Beclin-1
    Protein for Rat Beclin-1
    Protein for Rat Beclin-1
    Protein for Rat Beclin-1
    Protein for Rat Beclin-1
    Protein for Rat Beclin-1
    Protein for Rat Beclin-1

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    References
    1. 1.
      "Beclin mRNA in the developing rat ovary."
      Paredes A.H. , Tapia V. , Ojeda S.R.
      Submitted (2001-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Ovary.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
    3. 3.
      "Reduced expression of vacuole membrane protein 1 affects the invasion capacity of tumor cells."
      Sauermann M. , Sahin O. , Sultmann H. , Hahne F. , Blaszkiewicz S. , Majety M. , Zatloukal K. , Fuzesi L. , Poustka A. , Wiemann S. , Arlt D.
      Oncogene27:1320-1326(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH VMP1
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